4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL29038296

Cc1ccc(C(=O)O)cc1.O=Cc1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
SMN1; SMN2 Q16637 1/20 0.65
SRD5A2 P31213 3/20 0.59
CYP1B1 Q16678 1/20 0.56
CYP2A6 P11509 2/20 0.56
TRIM24 O15164 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
UNG P13051 1/20 0.53
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
MAPT P10636 2/20 0.51
POLB P06746 1/20 0.51
AKR1C3 P42330 1/20 0.50
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
DAO P14920 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL18406236 0.92 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2SRD5A2CYP1B1CYP2A6
Toluene SCHEMBL18406233 0.92 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2SRD5A2CYP1B1CYP2A6
Terephthalic Acid SCHEMBL5501539 0.92 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2SRD5A2CYP2A6TRIM24
4-Methylbenzoic Acid SCHEMBL11383447 0.92 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2SRD5A2CYP2A6TRIM24
Terephthalic Acid SCHEMBL11366672 0.92 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2SRD5A2CYP2A6TRIM24
4-Methylbenzoic Acid SCHEMBL11280739 0.92 ALDH1A1 (0.79) ALDH1A1SMN1; SMN2SRD5A2CYP2A6TRIM24
Methyl Benzoate SCHEMBL10871138 0.87 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2SRD5A2CYP1B1CES2
Benzaldehyde SCHEMBL3842987 0.87 CYP1B1 (0.54) ALDH1A1SMN1; SMN2CYP1B1CYP2A6CES2
Benzoic Acid SCHEMBL6157813 0.86 ALDH1A1 (0.74) ALDH1A1SRD5A2CYP1B1CYP2A6TRIM24
P-Xylene SCHEMBL28144631 0.85 CYP2A6 (0.75) ALDH1A1SMN1; SMN2CYP1B1CYP2A6CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283821-B Phencyclized propylamine compound, preparation method and application 郑州大学 2024-01-26 CN claimed
CN-116283821-A Phencyclized propylamine compound, preparation method and application 郑州大学 2023-06-23 CN claimed