SCHEMBL29038862

SCHEMBL29038862

O=C(O)C(O)CN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
CYP1A2 P05177 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
HDAC3 O15379 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
NCOR2 Q9Y618 2/20 0.42
POLB P06746 2/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16934693 1.00 PTPN1 (0.45) PTPN1CYP1A2MEN1KMT2ANPC1
SCHEMBL25345635 0.81 KDM4E (0.52) MEN1KMT2ANPC1RAB9ACA12
SCHEMBL7648267 0.81 KDM4E (0.52) MEN1KMT2ANPC1RAB9ACA12
SCHEMBL16932330 0.81 L3MBTL1 (0.47) PTPN1MEN1KMT2ANPC1RAB9A
SCHEMBL20162063 0.81 L3MBTL1 (0.47) PTPN1MEN1KMT2ANPC1RAB9A
SCHEMBL5798284 0.81 HDAC3 (0.46) PTPN1CYP1A2MEN1KMT2ANPC1
SCHEMBL2516271 0.80 L3MBTL1 (0.52) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL2516270 0.80 L3MBTL1 (0.52) MEN1KMT2ANPC1RAB9APOLB
SCHEMBL6227253 0.79 POLB (0.54) CYP1A2NPC1POLBALDH1A1NPSR1
SCHEMBL20400893 0.79 ALPI (0.58) PTPN1CYP1A2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483492-B Dipeptidyl peptidase I inhibitors 阿斯利康(瑞典)有限公司 2023-07-21 CN disclosed