Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL10617200 | 0.90 | — | — | |
| SCHEMBL10617160 | 0.84 | — | — | |
| Carbamic Acid SCHEMBL27856553 | 0.84 | — | — | |
| Methacrylic Acid SCHEMBL3287493 | 0.83 | TDP1 (0.41) | CYP1A2ALDH1A1LMNAPOLBMEN1 | |
| Acetone SCHEMBL594272 | 0.83 | — | — | |
| Carbamic Acid SCHEMBL28864494 | 0.81 | EPHX1 (0.42) | CYP1A2ALDH1A1LMNAEPHX1RECQL | |
| Methylcyclopentane SCHEMBL8746944 | 0.80 | EPHX1 (0.46) | CYP1A2ALDH1A1LMNAMEN1KMT2A | |
| Bicarbonate SCHEMBL4695324 | 0.78 | EPHX1 (0.50) | CYP1A2ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL2368 | 0.78 | — | — | |
| Bicarbonate SCHEMBL8913592 | 0.78 | EPHX1 (0.50) | CYP1A2ALDH1A1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225757-B | Preparation method of lobaplatin trihydrate | 昆明贵研药业有限公司 | 2023-07-21 | — | — | CN | disclosed |