SCHEMBL29039016

SCHEMBL29039016

Cc1nnc(Cl)cc1-c1c(F)cccc1F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 3/20 0.39
PDE10A Q9Y233 3/20 0.39
HSD11B1 P28845 1/20 0.35
KMT2A Q03164 2/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
HPGD P15428 1/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PTGES O14684 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ESR1 P03372 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MEN1 O00255 1/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30415229 1.00 PDE2A (0.39) PDE2APDE10AHSD11B1KMT2AADORA2A
SCHEMBL21543055 0.82 HSD11B1 (0.44) PDE2APDE10AHSD11B1KMT2AADORA2A
SCHEMBL30178120 0.81 MAOB (0.37) PDE2APDE10AHSD11B1KMT2AMAPT
SCHEMBL3937884 0.81 MAOB (0.37) PDE2APDE10AHSD11B1KMT2AMAPT
SCHEMBL23792999 0.72
SCHEMBL28028926 0.72 PDE2A (0.38) PDE2APDE10AHSD11B1KMT2AHPGD
SCHEMBL25230310 0.72 CYP1A2 (0.47) HSD11B1KMT2AHPGDMAPTLMNA
SCHEMBL29131813 0.71 PDE2A (0.36) PDE2APDE10AHSD11B1KMT2AADORA2A
SCHEMBL30414249 0.71 PDE2A (0.36) PDE2APDE10AHSD11B1KMT2AADORA2A
SCHEMBL3847246 0.69 KMT2A (0.40) PDE2APDE10AKMT2AHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN disclosed