Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 9/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 8/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.33 |
| ▸ | AKT2 | P31751 | 3/20 | 0.32 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | PRKACB | P22694 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25423156 | 0.83 | AKT1 (0.39) | CHEK1ROCK2ROCK1AKT2PRKACA | |
| SCHEMBL25424331 | 0.81 | MCL1 (0.39) | MCL1ROCK2ROCK1 | |
| SCHEMBL25424805 | 0.81 | ROCK2 (0.40) | ROCK2ROCK1 | |
| SCHEMBL29039234 | 0.80 | ROCK2 (0.36) | CHEK1ROCK2ROCK1AKT2PRKACA | |
| SCHEMBL25423833 | 0.79 | MCL1 (0.37) | MCL1ROCK2ROCK1AKT1 | |
| SCHEMBL25425745 | 0.78 | ROCK2 (0.35) | MCL1ROCK2ROCK1 | |
| SCHEMBL25426311 | 0.77 | CHEK1 (0.33) | CHEK1ROCK2ROCK1 | |
| SCHEMBL25422539 | 0.76 | MCL1 (0.33) | MCL1ROCK2ROCK1 | |
| SCHEMBL25425205 | 0.72 | AURKA (0.35) | ROCK2ROCK1AKT2AKT1 | |
| SCHEMBL26998207 | 0.71 | MAP3K14 (0.37) | ROCK2ROCK1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234802-A | Quinoline CGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2023-06-06 | — | — | CN | disclosed |