Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26999281 | 1.00 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL29410731 | 1.00 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL20002164 | 0.86 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL9078951 | 0.86 | HSD17B10 (0.44) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL7381169 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL19545913 | 0.85 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL31758003 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL20334461 | 0.85 | HSD17B10 (0.46) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL6529031 | 0.85 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 | |
| SCHEMBL18782375 | 0.85 | HSD17B10 (0.41) | HSD17B10SMN1; SMN2NPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116234802-A | Quinoline CGAS antagonist compounds | 免疫传感器治疗股份有限公司 | 2023-06-06 | — | — | CN | disclosed |