SCHEMBL6529031

SCHEMBL6529031

CC(C)(C)OC(=O)N1CCC[C@H]1C(O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 1/20 0.39
KLK7 P49862 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758003 1.00 HSD17B10 (0.49) HSD17B10SMN1; SMN2KMT2APOLBNPC1
SCHEMBL7381169 1.00 HSD17B10 (0.49) HSD17B10SMN1; SMN2KMT2APOLBNPC1
SCHEMBL22139321 0.86 HSD17B10 (0.49) HSD17B10SMN1; SMN2KMT2ANPC1ALDH1A1
SCHEMBL20256229 0.86 HSD17B10 (0.49) HSD17B10SMN1; SMN2KMT2ANPC1ALDH1A1
SCHEMBL29039375 0.85 HSD17B10 (0.44) HSD17B10SMN1; SMN2KMT2ANPC1ALDH1A1
SCHEMBL26999281 0.85 HSD17B10 (0.44) HSD17B10SMN1; SMN2KMT2ANPC1ALDH1A1
SCHEMBL29410731 0.85 HSD17B10 (0.44) HSD17B10SMN1; SMN2KMT2ANPC1ALDH1A1
SCHEMBL31351949 0.85 HSD17B10 (0.49) HSD17B10SMN1; SMN2KMT2APOLBNPC1
SCHEMBL25215473 0.84 HSD17B10 (0.48) HSD17B10SMN1; SMN2KMT2APOLBNPC1
SCHEMBL19637426 0.84 HSD17B10 (0.48) HSD17B10SMN1; SMN2KMT2APOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
WO-2005037828-A1 NOVEL INHIBITORS OF DPP-IV, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT LG LIFE SCIENCES LTD. (KR) 2005-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 HSD17B10 148/4885SMN1; SMN2 1910/4885KMT2A 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.