Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29039461 | 1.00 | NPC1 (0.39) | NPC1THRATHRBLCKPPARD | |
| SCHEMBL22123616 | 0.95 | LCK (0.36) | NPC1THRATHRBLCKPPARD | |
| SCHEMBL25355957 | 0.79 | NPC1 (0.43) | NPC1NAAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25355953 | 0.79 | NPC1 (0.43) | NPC1NAAASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10958425 | 0.79 | GABRR1 (0.39) | NPC1NAAAEPHX1 | |
| SCHEMBL25356906 | 0.76 | GRIN2D (0.41) | NPC1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL25356903 | 0.76 | GRIN2D (0.41) | NPC1ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL22124023 | 0.75 | L3MBTL1 (0.33) | ALDH1A1TSHREPHX1 | |
| SCHEMBL2781272 | 0.71 | NPC1 (0.45) | NPC1THRATHRBALDH1A1NAAA | |
| Bicarbonate SCHEMBL3831269 | 0.71 | NPC1 (0.45) | NPC1THRATHRBALDH1A1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262735-B | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-116262724-B | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2025-04-29 | — | — | CN | disclosed |
| CN-116262735-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-116262724-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |