Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903206 | 0.83 | GRM2 (0.41) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15498499 | 0.76 | SRC (0.47) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27909230 | 0.74 | CHRNB2 (0.44) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL10233103 | 0.72 | MAPT (0.49) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL17689141 | 0.72 | MAPT (0.49) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL17115672 | 0.71 | AOC3 (0.46) | MAPTMEN1KMT2AALDH1A1HRH3 | |
| SCHEMBL151047 | 0.70 | MAPT (0.46) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL148390 | 0.69 | MAPT (0.49) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL151160 | 0.69 | MAPT (0.49) | CHRNB2CHRNA4MAPTMEN1KMT2A | |
| SCHEMBL30117237 | 0.69 | KMT2A (0.44) | MAPTMEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262739-A | Nitrogen-containing aryl derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |