Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.50 |
| ▸ | TUBB | P07437 | 2/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11493595 | 0.88 | KDM4E (0.54) | PTGS2PTGS1KDM4EMAPTKMT2A | |
| SCHEMBL13024122 | 0.83 | ESR1 (0.60) | PTGS2KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL29039706 | 0.82 | PTGS2 (0.52) | PTGS2MAPTHPGDTUBB4ATUBB | |
| Indoxole SCHEMBL42592 | 0.82 | PTGS2 (0.76) | PTGS2PTGS1KDM4EMAPTKMT2A | |
| Indoxole SCHEMBL29519430 | 0.82 | PTGS2 (0.76) | PTGS2PTGS1KDM4EMAPTKMT2A | |
| SCHEMBL820614 | 0.81 | MAPK14 (0.55) | PTGS2KDM4EMAPTTUBB4ATUBB | |
| SCHEMBL7039067 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1KDM4EMAPTKMT2A | |
| SCHEMBL7042910 | 0.79 | PTGS2 (0.72) | PTGS2PTGS1KDM4EMAPTKMT2A | |
| SCHEMBL31053083 | 0.79 | KDM4E (0.57) | PTGS2PTGS1KDM4EMAPTKMT2A | |
| SCHEMBL1637807 | 0.79 | KDM4E (0.57) | PTGS2PTGS1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082214-A | 2-aryl-3-tert-butylindole compound, preparation method and application thereof | 常州大学 | 2023-05-09 | — | — | CN | disclosed |