SCHEMBL29040201

SCHEMBL29040201

c1ccc(Cc2ccccc2-c2ccccc2-c2ccccc2Cc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.55
HTR2A P28223 1/20 0.52
BCL2 P10415 1/20 0.50
BCL2L1 Q07817 1/20 0.50
BRD4 O60885 1/20 0.44
ALOX5 P09917 1/20 0.43
ELANE P08246 1/20 0.43
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KEAP1 Q14145 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6229874 0.97 CALM1 (0.58) CALM1HTR2ABCL2BCL2L1BRD4
SCHEMBL28825976 0.91 DPP4 (0.48) CALM1HTR2ABCL2BCL2L1BRD4
SCHEMBL11197981 0.86 SMN1; SMN2 (0.50) CALM1HTR2ABCL2BCL2L1BRD4
SCHEMBL10824453 0.86 TP53 (0.48) CALM1HTR2ABCL2BCL2L1BRD4
SCHEMBL31070319 0.85 DPP4 (0.58) CALM1HTR2ABCL2BCL2L1HPGD
SCHEMBL340250 0.85 DPP4 (0.58) CALM1HTR2ABCL2BCL2L1HPGD
SCHEMBL8056666 0.84 BCL2L1 (0.57) CALM1HTR2ABCL2BCL2L1ALOX5
SCHEMBL9419606 0.84 CALM1 (0.44) CALM1HTR2ABCL2BCL2L1BRD4
Hydrogen Sulfide SCHEMBL27779487 0.83 DPP4 (0.56) CALM1HTR2ABCL2BCL2L1ELANE
SCHEMBL972711 0.83 CALM1 (0.69) CALM1HTR2ABCL2BCL2L1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116490495-A Triazine or pyrimidine derivative and organic electroluminescent device comprising same 株式会社乐普拓 2023-07-25 CN disclosed