Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29040308 | 1.00 | SRC (0.44) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL24313085 | 0.87 | BTK (0.56) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL18904876 | 0.87 | BTK (0.56) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL17426129 | 0.81 | BTK (0.51) | BTKGPR119MEN1ALDH1A1MAPT | |
| SCHEMBL29040309 | 0.79 | BTK (0.48) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL28541403 | 0.79 | BTK (0.48) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL29040307 | 0.79 | BTK (0.48) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL28541404 | 0.79 | BTK (0.48) | SRCEGFRBTKGPR119MEN1 | |
| SCHEMBL22822832 | 0.74 | SRC (0.47) | SRCEGFRBTKGPR119USP30 | |
| SCHEMBL22822757 | 0.74 | SRC (0.47) | SRCEGFRBTKGPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096720-A | Dihydropyrrolo [2,3-d ] pyridazin-7-one derivatives, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |