Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | ABL2 | P42684 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29040309 | 1.00 | BTK (0.48) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL28541403 | 0.88 | BTK (0.48) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL28541404 | 0.88 | BTK (0.48) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL24313466 | 0.87 | BTK (0.63) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL24313086 | 0.82 | BTK (0.46) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL29040306 | 0.79 | SRC (0.44) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL29040308 | 0.79 | SRC (0.44) | BTKSRCEGFRGPR119MEN1 | |
| SCHEMBL23567188 | 0.76 | BTK (0.82) | BTKSRCEGFRGPR119ABL1 | |
| SCHEMBL21482522 | 0.76 | BTK (0.82) | BTKSRCEGFRGPR119ABL1 | |
| SCHEMBL17426108 | 0.75 | BTK (0.63) | BTKSRCEGFRGPR119MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096720-A | Dihydropyrrolo [2,3-d ] pyridazin-7-one derivatives, preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |