Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 6/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116265 | 1.00 | MAPK1 (0.68) | MAPK1RECQLTSHRGAAMEN1 | |
| SCHEMBL3181108 | 0.92 | MAPK1 (0.55) | MAPK1RECQLTSHRGAAMEN1 | |
| SCHEMBL3181095 | 0.92 | MAPK1 (0.55) | MAPK1RECQLTSHRGAAMEN1 | |
| SCHEMBL4221613 | 0.88 | RECQL (0.77) | RECQLTSHRGAAMEN1KMT2A | |
| SCHEMBL30506314 | 0.88 | RECQL (0.77) | RECQLTSHRGAAMEN1KMT2A | |
| SCHEMBL1660322 | 0.88 | RECQL (0.77) | RECQLTSHRGAAMEN1KMT2A | |
| SCHEMBL30506235 | 0.81 | RECQL (0.50) | MAPK1RECQLTSHRGAAMEN1 | |
| SCHEMBL29040359 | 0.81 | RECQL (0.50) | MAPK1RECQLGAAMEN1KMT2A | |
| SCHEMBL30506256 | 0.81 | RECQL (0.50) | MAPK1RECQLTSHRGAAMEN1 | |
| SCHEMBL20116382 | 0.81 | RECQL (0.50) | MAPK1RECQLTSHRGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777121-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-110099898-B | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2023-07-25 | — | — | CN | disclosed |