Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 1.00 |
| ▸ | TOP2B | Q02880 | 2/20 | 1.00 |
| ▸ | MMP1 | P03956 | 15/20 | 0.70 |
| ▸ | MMP2 | P08253 | 15/20 | 0.70 |
| ▸ | MMP9 | P14780 | 15/20 | 0.70 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.70 |
| ▸ | EGFR | P00533 | 5/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29040338 | 1.00 | TOP2A (1.00) | TOP2ATOP2BMMP1MMP2MMP9 | |
| SCHEMBL3015874 | 0.86 | TOP2A (0.76) | TOP2ATOP2BMMP1MMP2MMP9 | |
| SCHEMBL3015879 | 0.86 | TOP2A (0.76) | TOP2ATOP2BMMP1MMP2MMP9 | |
| SCHEMBL9988800 | 0.83 | MMP1 (1.00) | TOP2ATOP2BMMP1MMP2MMP9 | |
| SCHEMBL9988799 | 0.83 | MMP1 (1.00) | TOP2ATOP2BMMP1MMP2MMP9 | |
| SCHEMBL11590995 | 0.80 | EGFR (0.92) | TOP2AMMP1MMP2MMP9DEGS1 | |
| N-Phenylcinnamamide SCHEMBL4205896 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9DEGS1EGFR | |
| N-Phenylcinnamamide SCHEMBL3667414 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9DEGS1EGFR | |
| N-Phenylcinnamamide SCHEMBL2682029 | 0.77 | MMP1 (1.00) | MMP1MMP2MMP9DEGS1EGFR | |
| SCHEMBL9990629 | 0.76 | MMP1 (1.00) | MMP1MMP2MMP9DEGS1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260052-B | 2-phenyl naphthalene derivative and preparation method and application thereof | 山东大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-115260052-A | 2-phenylnaphthalene derivative and preparation method and application thereof | 山东大学 | 2022-11-01 | — | — | CN | disclosed |