Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30457557 | 1.00 | HPGD (0.46) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL22075920 | 0.92 | PARP1 (0.45) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL22075950 | 0.91 | PARP1 (0.46) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL22075934 | 0.90 | PARP1 (0.47) | PARP1PARP2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL22075954 | 0.90 | PARP1 (0.47) | PARP1PARP2HSD17B10ALDH1A1MEN1 | |
| SCHEMBL22111194 | 0.89 | PDK2 (0.42) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL22075928 | 0.87 | PARP1 (0.43) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL22075936 | 0.87 | PARP1 (0.43) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL22075944 | 0.84 | POLB (0.44) | HPGDPARP1PARP2HSD17B10ALDH1A1 | |
| SCHEMBL23499604 | 0.82 | PARP1 (0.52) | HPGDPARP1PARP2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444494-A | Compound for targeted degradation of BUB1B and BUB1 protein, and preparation method and application thereof | 浙江大学 | 2023-07-18 | — | — | CN | disclosed |