Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525285 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL133020 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL598026 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL3422180 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL5133849 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL2819924 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL7908254 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL5193445 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL15508929 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA | |
| SCHEMBL22777078 | 1.00 | TDP1 (1.00) | TDP1MAOAMAOBMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444494-A | Compound for targeted degradation of BUB1B and BUB1 protein, and preparation method and application thereof | 浙江大学 | 2023-07-18 | — | — | CN | disclosed |