SCHEMBL133020

SCHEMBL133020

CC(C)(C)OC(=O)NCCCCCO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 1.00
MAOA P21397 1/20 0.63
MAOB P27338 1/20 0.63
MEN1 O00255 1/20 0.59
GAA P10253 1/20 0.59
KMT2A Q03164 1/20 0.59
CA12 O43570 6/20 0.58
CA1 P00915 6/20 0.58
CA2 P00918 6/20 0.58
CA9 Q16790 6/20 0.58
ACHE P22303 6/20 0.50
EPHX1 P07099 1/20 0.46
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7525285 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL598026 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL3422180 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL5133849 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL2819924 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL7908254 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL5193445 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL15508929 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL22777078 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA
SCHEMBL29040489 1.00 TDP1 (1.00) TDP1MAOAMAOBMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7223851-B2 Nucleic acid-binding polymers GENERAL DYNAMICS ADVANCED INFORMATION SYSTEMS, INC. (US) 2007-05-29 US claimed
US-20040157217-A1 Nucleic acid-binding polymers VERIDIAN SYSTEMS DIVISION 2004-08-12 US claimed
EP-4003988-B1 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS SERVIER LAB (FR) 2026-05-20 EP disclosed
WO-2026087635-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 EP disclosed
US-20260092061-A1 COMPOUNDS FOR TARGETED PROTEIN DEGRADATION AMPHISTA THERAPEUTICS LTD (GB) 2026-04-02 US disclosed
US-20260085062-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-26 US disclosed
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-12 US disclosed
US-20260055097-A9 NRF2 PROTEIN DEGRADERS GANYMEDE ONCOLOGY INC (US) 2026-02-26 US disclosed
US-20260041776-A1 POLYMER CONTRAST AGENT KOWA COMPANY, LTD. (JP) 2026-02-12 US disclosed
US-12517130-B2 Isoindoline derivatives which bind to an ATP binding site Neophore Limited (GB) 2026-01-06 US disclosed
WO-1995032954-A1 EPOXYSUCCINIC ACID DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-12-07 WO disclosed
WO-1995018105-A1 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS SANOFI (FR) 1995-07-06 WO disclosed
EP-0521827-A1 Pharmacological active hydrazin derivatives and process for their preparation CIBA-GEIGY AG (CH) 1993-01-07 EP disclosed
US-5047430-A Glutamate Receptor Inhibitors TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-10 US disclosed
EP-0278621-B1 SUBSTITUTED AMINE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1991-06-12 EP disclosed
US-4990511-A Amide compounds, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-05 US disclosed
EP-0353753-A1 Amide compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-02-07 EP disclosed
EP-0339927-A2 Amide compounds their production and use Takeda Chemical Industries, Ltd. (JP) 1989-11-02 EP disclosed
EP-0229944-A2 Novel tetrahydroisoquinoline derivatives SYNTEX (U.S.A.) INC. (US) 1987-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041776-A1 POLYMER CONTRAST AGENT RXFP3, HAX1, MSR1 TDP1 2333/4885MAOA 3051/4885MAOB 3518/4885
US-20260092061-A1 COMPOUNDS FOR TARGETED PROTEIN DEGRADATION BCL9L, RBBP9, BRD9 TDP1 3638/4885MAOA 3362/4885MAOB 3364/4885
US-20260085062-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK1G1, CSNK2A3 TDP1 2279/4885MAOA 4461/4885MAOB 4211/4885
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK2A3, CSNK1G1 TDP1 2438/4885MAOA 4502/4885MAOB 4075/4885
US-20260055097-A9 NRF2 PROTEIN DEGRADERS KEAP1, NFE2L2, NFE2 TDP1 3181/4885MAOA 2140/4885MAOB 2300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.