Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047901 | 0.81 | SLC6A4 (0.54) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL30032791 | 0.81 | SLC6A4 (0.54) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL168782 | 0.81 | SLC6A4 (0.54) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL3664220 | 0.80 | CYP1B1 (0.43) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL30129727 | 0.80 | CYP1B1 (0.43) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL4038396 | 0.80 | CYP1B1 (0.43) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL497994 | 0.79 | SLC6A4 (0.56) | CYP1B1ALDH1A1HSD17B10DRD2SLC6A4 | |
| SCHEMBL9473311 | 0.79 | CYP1B1 (0.42) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL11243776 | 0.79 | CYP1B1 (0.42) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 | |
| SCHEMBL7648672 | 0.79 | CYP2A6 (0.47) | CYP1B1ALDH1A1HSD17B10CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260096-A | Method for synthesizing dihydroisoquinolinone compound based on carbon monoxide gas or carbon monoxide alternative source | 武汉大学 | 2022-11-01 | — | — | CN | disclosed |