Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168782 | 1.00 | SLC6A4 (0.54) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL30032791 | 1.00 | SLC6A4 (0.54) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL497994 | 0.98 | SLC6A4 (0.56) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL3968194 | 0.94 | SLC6A4 (0.56) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL30477104 | 0.89 | SLC6A4 (0.59) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL248440 | 0.89 | SLC6A4 (0.59) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL7746921 | 0.89 | HPRT1 (0.50) | SLC6A4DRD2MTNR1AKDM1AHRH3 | |
| SCHEMBL23301397 | 0.85 | HPRT1 (0.50) | SLC6A4DRD2MTNR1AKDM1ACYP1B1 | |
| SCHEMBL6567045 | 0.82 | HPRT1 (0.52) | SLC6A4DRD2MTNR1AKDM1ACYP1B1 | |
| SCHEMBL30129727 | 0.82 | CYP1B1 (0.43) | SLC6A4DRD2KDM1ACYP1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621181-A | Star-shaped tetramine derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2022-06-14 | — | — | CN | disclosed |
| EP-2076506-A2 | HETEROCYCLIC-SUBSTITUTED PIPERIDINES AS ORL-1 LIGANDS | Purdue Pharma L.P. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008089201-A2 | HETEROCYCLIC-SUBSTITUTED PIPERIDINE AS ORL-1 LIGANDS | PURDUE PHARMA L.P. (US) | 2008-07-24 | — | — | WO | disclosed |