Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.42 |
| ▸ | PARP1 | P09874 | 3/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1633353 | 0.84 | PIM1 (0.42) | PIM1PIM2PARP1BRD4PIK3CD | |
| SCHEMBL27787945 | 0.77 | PIM1 (0.43) | PIM1PIM2PARP1BRD4PIK3CD | |
| SCHEMBL3030442 | 0.74 | PIM1 (0.40) | PIM1PIM2BRD4 | |
| SCHEMBL3020648 | 0.71 | BRD4 (0.39) | PIM1PIM2BRD4 | |
| SCHEMBL3020645 | 0.71 | BRD4 (0.39) | PIM1PIM2BRD4 | |
| SCHEMBL13387485 | 0.71 | BRD4 (0.38) | PIM1PIM2BRD4 | |
| SCHEMBL13103261 | 0.71 | BRD4 (0.31) | BRD4 | |
| SCHEMBL3031799 | 0.69 | BRD4 (0.37) | PIM1PIM2BRD4PIK3CD | |
| SCHEMBL3031795 | 0.69 | BRD4 (0.37) | PIM1PIM2BRD4PIK3CD | |
| SCHEMBL3026724 | 0.69 | BRD4 (0.38) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |