Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29041986 | 0.93 | PIK3CD (0.41) | PIK3CDIRAK4PDE4DMAPK1CHRM2 | |
| SCHEMBL29042117 | 0.93 | PIK3CD (0.41) | PIK3CDIRAK4PDE4DMAPK1CHRM2 | |
| SCHEMBL30122245 | 0.92 | PIK3CD (0.47) | PIK3CDPDE4DMAPK1PDE1APDE1B | |
| SCHEMBL29041973 | 0.89 | LRRK2 (0.40) | PIK3CDKCNH2LRRK2WNT1GSK3B | |
| SCHEMBL26757187 | 0.84 | PIK3CD (0.40) | PIK3CDPDE4DMAPK1PDE1APDE1B | |
| SCHEMBL21175144 | 0.84 | PIK3CD (0.40) | PIK3CDPDE4DMAPK1PDE1APDE1B | |
| SCHEMBL20014996 | 0.84 | PIK3CD (0.40) | PIK3CDPDE4DMAPK1PDE1APDE1B | |
| SCHEMBL29042016 | 0.83 | SCD (0.37) | CHRM1KCNH2SCDMBTD1L3MBTL3 | |
| SCHEMBL13468 | 0.82 | HDAC8 (0.39) | PIK3CDKCNH2SCD | |
| SCHEMBL19279630 | 0.81 | PIK3CD (0.55) | PIK3CDPDE4DMAPK1PDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |