Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 7/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29042018 | 0.83 | PIK3CD (0.42) | SCDKCNH2MBTD1L3MBTL3CHRM1 | |
| SCHEMBL31482815 | 0.82 | KMO (0.40) | SCDKDM5AKDM4CKDM5BTEAD1 | |
| SCHEMBL29041973 | 0.81 | LRRK2 (0.40) | SCDKCNH2GPR119 | |
| SCHEMBL13468 | 0.80 | HDAC8 (0.39) | SCDHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL30613532 | 0.79 | IRAK4 (0.37) | SCDHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL29041994 | 0.79 | IRAK4 (0.37) | SCDHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL26683794 | 0.78 | HTR1A (0.46) | SCDHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL25045382 | 0.78 | HTR7 (0.39) | SCDHTR2AHTR7KCNH2GPR119 | |
| SCHEMBL17678127 | 0.78 | PDE9A (0.38) | SCDHTR2AHTR7KCNH2DRD2 | |
| SCHEMBL29042132 | 0.78 | HTR7 (0.41) | SCDHTR2AHTR7KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116478145-B | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023198114-A1 | ALK2 KINASE INHIBITOR | 杭州邦顺制药有限公司 | 2023-10-19 | — | — | WO | disclosed |
| CN-116478145-A | ALK2 kinase inhibitors | 杭州邦顺制药有限公司 | 2023-07-25 | — | — | CN | disclosed |