Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | USP1 | O94782 | 6/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461987 | 1.00 | CCNE2 (0.41) | CCNE2CCNE1CDK2USP1WDR48 | |
| SCHEMBL25978533 | 0.84 | USP1 (0.50) | CCNE2CCNE1CDK2USP1MAPT | |
| SCHEMBL31423513 | 0.78 | USP1 (0.42) | USP1WDR48 | |
| SCHEMBL29043870 | 0.78 | USP1 (0.42) | USP1PDE2A | |
| SCHEMBL30462032 | 0.78 | USP1 (0.42) | USP1PDE2A | |
| SCHEMBL30462007 | 0.76 | USP1 (0.44) | USP1PDE2A | |
| SCHEMBL29043928 | 0.76 | USP1 (0.44) | USP1PDE2A | |
| SCHEMBL30462073 | 0.76 | USP1 (0.50) | USP1WDR48MAPTTP53 | |
| SCHEMBL29043879 | 0.76 | USP1 (0.50) | USP1WDR48MAPTTP53 | |
| SCHEMBL30462034 | 0.76 | USP1 (0.39) | CCNE2CCNE1CDK2USP1WDR48 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496252-A | Pyrimidine compound, preparation method and medical application thereof | 江苏亚虹医药科技股份有限公司 | 2023-07-28 | — | — | CN | disclosed |