Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044452 | 0.86 | TP53 (0.70) | KDM4ESMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL4566590 | 0.85 | SMN1; SMN2 (0.65) | KDM4ESMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL29044451 | 0.83 | MAPT (0.51) | KDM4ESMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL29044454 | 0.83 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL3582251 | 0.81 | SMN1; SMN2 (1.00) | KDM4ESMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL29044468 | 0.80 | SMN1; SMN2 (0.59) | KDM4ESMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL29044465 | 0.74 | MAPT (0.50) | KDM4ESMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL29044466 | 0.74 | MAPT (0.65) | KDM4ESMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL29044494 | 0.74 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2HTTALDH1A1LMNA | |
| SCHEMBL3589387 | 0.73 | SMN1; SMN2 (0.70) | KDM4ESMN1; SMN2HTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116531373-A | Thiazole compound, pharmaceutical composition and application thereof | 上海日馨医药科技股份有限公司 | 2023-08-04 | — | — | CN | disclosed |