Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482931 | 0.80 | CES2 (0.65) | CES2CES1KDM4ELMNAGAA | |
| SCHEMBL80721 | 0.80 | CES2 (0.65) | CES2CES1KDM4ELMNAGAA | |
| Bromide SCHEMBL31218183 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL28526382 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| SCHEMBL4880434 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| Hydrochloric Acid SCHEMBL4376678 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| SCHEMBL31376156 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| SCHEMBL31376157 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| SCHEMBL2392049 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA | |
| Water SCHEMBL27623262 | 0.78 | CES2 (0.62) | CES2CES1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535392-B | Preparation method of oxo-pyridine compound, intermediate and application | 成都施贝康生物医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116621742-A | Novel preparation method of oxo-pyridine compound and key intermediate | 成都施贝康生物医药科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116621728-A | Novel preparation method of oxo-pyridine compound and key intermediate | 成都施贝康生物医药科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116535392-A | Preparation method of oxo-pyridine compound, intermediate and application | 成都施贝康生物医药科技有限公司 | 2023-08-04 | — | — | CN | disclosed |