Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31347645 | 0.79 | APP (0.61) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2395706 | 0.79 | APP (0.61) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL3344881 | 0.79 | APP (0.54) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL11803092 | 0.79 | APP (0.54) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL29161478 | 0.78 | APP (0.68) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL1621890 | 0.78 | APP (0.56) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL13982514 | 0.76 | APP (0.70) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL12282183 | 0.76 | APP (0.70) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL12322087 | 0.76 | APP (1.00) | APPALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL196018 | 0.76 | KDM4E (0.58) | APPALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535410-A | Triazoloquinazolinone compound and application thereof | 河北农业大学 | 2023-08-04 | — | — | CN | claimed |
| CN-116535410-B | Triazoloquinazolinone compound and application thereof | 河北农业大学 | 2025-03-21 | — | — | CN | disclosed |
| CN-116535410-A | Triazoloquinazolinone compound and application thereof | 河北农业大学 | 2023-08-04 | — | — | CN | disclosed |