Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29844822 | 1.00 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| Pyrazole SCHEMBL28116372 | 0.86 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL2222578 | 0.77 | TYMS (0.50) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL6099088 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL554709 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL1621540 | 0.76 | GAA (0.50) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL6076792 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL3139711 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL4413903 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL530191 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | ZHEJIANG UNIVERSITY (CN) | 2025-09-02 | — | — | US | claimed |
| CN-117209437-A | Preparation method of aminoquinazolinone derivative | 宁夏大学 | 2023-12-12 | — | — | CN | claimed |
| CN-109503550-B | 2-azaaryl-6-substituted amino quinazolinone compound and preparation method and application thereof | 江西师范大学 | 2022-11-29 | — | — | CN | claimed |
| US-20220017505-A1 | AMINOQUINAZOLINONE AND AMINOISOQUINOLINONE DERIVATIVES AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-01-20 | — | — | US | claimed |
| EP-3904343-A1 | AMINO QUINAZOLINONE, AMINO ISOQUINOLONE DERIVATIVES AND APPLICATION THEREOF | Zhejiang University (CN) | 2021-11-03 | — | — | EP | claimed |
| CN-109516961-B | Aminoquinazolinone and aminoisoquinolinone derivatives and uses thereof | 浙江大学 | 2021-01-01 | — | — | CN | claimed |
| WO-2020134921-A1 | AMINO QUINAZOLINONE, AMINO ISOQUINOLONE DERIVATIVES AND APPLICATION THEREOF | 浙江大学 | 2020-07-02 | — | — | WO | claimed |
| CN-109516961-A | Aminoquinazolinone and aminoisoquinoline ketone derivatives and its application | 浙江大学 | 2019-03-26 | — | — | CN | claimed |
| CN-1302801-B | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHOU NOHYAKU CO LTD | 2013-03-20 | — | — | CN | claimed |
| US-8034931-B2 | Process for producing substituted aminoquinazolinone derivative, intermediate therefor, and pest control agent | NIHON NOHYAKU CO., LTD. (JP) | 2011-10-11 | — | — | US | claimed |
| CN-1092188-C | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHON NOHYAKU CO LTD (JP) | 2002-10-09 | — | — | CN | claimed |
| US-6455535-B1 | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 2002-09-24 | — | — | US | claimed |
| EP-0735035-B1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-06-05 | — | — | EP | claimed |
| CN-1302801-A | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHOU NOHYAKU CO LTD (JP) | 2001-07-11 | — | — | CN | claimed |
| EP-1097932-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 2001-05-09 | — | — | EP | claimed |
| CN-1282517-A | Pest controlling agent containing substituted aminoquinazolone or thioketone derivative or its salt as active component | NIHON NOHYAKU CO LTD (JP) | 2001-02-07 | — | — | CN | claimed |
| EP-0987255-A2 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2000-03-22 | — | — | EP | claimed |
| US-5714492-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1998-02-03 | — | — | US | claimed |
| CN-1134933-A | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHON NOHYAKU CO LTD (JP) | 1996-11-06 | — | — | CN | claimed |
| EP-0735035-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12404269-B2 | Aminoquinazolinone and aminoisoquinolinone derivatives and application thereof | PIK3R5, PIK3CA, PIK3R1 | KDM4E 1579/4885ALDH1A1 2788/4885HSD17B10 1294/4885 |
| US-20220017505-A1 | AMINOQUINAZOLINONE AND AMINOISOQUINOLINONE DERIVATIVES AND APPLICATION THEREOF | PIK3R5, PIK3CA, PIK3R1 | KDM4E 1579/4885ALDH1A1 2788/4885HSD17B10 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.