SCHEMBL29044898

SCHEMBL29044898

c1ccc(N(c2ncncn2)c2ncc[nH]2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 6/20 0.41
TSHR P16473 2/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 1/20 0.37
GLA P06280 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MTOR P42345 1/20 0.37
ADK P55263 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
POLB P06746 1/20 0.32
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3240001 0.90 TAAR1 (0.45) TAAR1TSHRCYP2D6LMNAGLA
SCHEMBL30515454 0.87 TAAR1 (0.41) TAAR1TSHRCYP2D6LMNAGLA
SCHEMBL10275189 0.84 TAAR1 (0.49) TAAR1TSHRCYP2D6LMNAGLA
SCHEMBL4399532 0.78 ALDH1A1 (0.48) TSHRCYP2D6LMNASMN1; SMN2ALDH1A1
SCHEMBL12460477 0.70 ALDH1A1 (0.42) TSHRCYP2D6LMNASMN1; SMN2ALDH1A1
SCHEMBL8612344 0.70 TAAR1 (0.53) TAAR1TSHRCYP2D6LMNAGLA
SCHEMBL19209978 0.70 ALDH1A1 (0.43) TAAR1SMN1; SMN2MTORADKNISCH
SCHEMBL4582422 0.68 TDP1 (0.54) TSHRCYP2D6LMNABLMSMN1; SMN2
SCHEMBL5775644 0.67 TAAR1 (0.41) TAAR1TSHRCYP2D6LMNAGLA
SCHEMBL5775648 0.67 TAAR1 (0.41) TAAR1TSHRCYP2D6LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340814-B Preparation and application of cationic polyurethane antibacterial coating 苏州邦得纳米涂层科技有限公司 2023-08-01 CN disclosed