Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045174 | 0.83 | CHEK1 (0.47) | CHEK1KCNH2HSD17B10DYRK1AKMT2A | |
| SCHEMBL24936161 | 0.79 | KCNH2 (0.66) | CHEK1KCNH2DYRK1A | |
| SCHEMBL30522667 | 0.79 | KCNH2 (0.66) | CHEK1KCNH2DYRK1A | |
| SCHEMBL29045194 | 0.75 | CYP1A2 (0.35) | CHEK1IKBKBKMT2AGAAIRAK4 | |
| SCHEMBL24936259 | 0.72 | KCNH2 (0.50) | CHEK1KCNH2HSD17B10IRAK4 | |
| SCHEMBL24936150 | 0.71 | KCNH2 (0.57) | CHEK1KCNH2DYRK1A | |
| SCHEMBL29045150 | 0.68 | CYP1A2 (0.35) | IKBKBKMT2AGAAIRAK4MEN1 | |
| SCHEMBL24936266 | 0.67 | KCNH2 (0.53) | KCNH2DYRK1A | |
| SCHEMBL24936205 | 0.66 | CHEK1 (0.44) | CHEK1KCNH2HSD17B10KMT2AMEN1 | |
| SCHEMBL24945078 | 0.66 | KCNH2 (0.51) | CHEK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116546974-A | 5-heteroaryl-1H-pyrazol-3-amine derivatives | 住友制药株式会社 | 2023-08-04 | — | — | CN | disclosed |