Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637089 | 0.92 | TDP1 (0.64) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7640034 | 0.88 | TDP1 (0.58) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7636953 | 0.86 | TDP1 (0.57) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7636485 | 0.86 | TDP1 (0.57) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7426974 | 0.85 | TDP1 (1.00) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL5523873 | 0.84 | TDP1 (0.70) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL28275182 | 0.81 | MTNR1A (0.56) | TDP1KMT2ARAB9AMAPTPPARG | |
| SCHEMBL7429207 | 0.81 | TDP1 (0.91) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7430736 | 0.81 | TDP1 (0.91) | TDP1L3MBTL1MAPK1TSHRALDH1A1 | |
| SCHEMBL7571535 | 0.80 | TDP1 (0.88) | TDP1L3MBTL1MAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083934-A1 | N-ACETYLGALACTOSAMINE (GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2024-03-14 | — | — | US | disclosed |
| EP-4225322-A1 | N-ACETYLGALACTOSAMINE(GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | Adarx Pharmaceuticals, Inc. (US) | 2023-08-16 | — | — | EP | disclosed |
| CN-116546989-A | N-acetylgalactosamine (GalNAc) derived compounds and oligonucleotides | 阿达尔克斯制药有限公司 | 2023-08-04 | — | — | CN | disclosed |
| WO-2022076922-A1 | N-ACETYLGALACTOSAMINE(GAlNAc)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | ADARX PHARMACEUTICALS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083934-A1 | N-ACETYLGALACTOSAMINE (GALNAC)-DERIVED COMPOUNDS AND OLIGONUCLEOTIDES | GALNT1, GALNT13, GALNT6 | TDP1 667/4885L3MBTL1 223/4885MAPK1 3371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.