Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 3/20 | 0.67 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994223 | 0.85 | KDM4E (0.47) | GRNSORT1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12612042 | 0.82 | KDM4E (0.45) | GRNSORT1KDM4EMAPTALDH1A1 | |
| SCHEMBL2449044 | 0.82 | KDM4E (0.61) | GRNSORT1KDM4EMAPTLMNA | |
| SCHEMBL8260077 | 0.80 | GRN (0.73) | GRNSORT1KDM4EMAPTLMNA | |
| SCHEMBL1572486 | 0.80 | GRN (1.00) | GRNSORT1KDM4EMAPTLMNA | |
| SCHEMBL5966743 | 0.80 | GRN (0.58) | GRNSORT1KDM4EMAPTLMNA | |
| SCHEMBL7985728 | 0.79 | KDM4E (0.67) | GRNSORT1KDM4EMAPTLMNA | |
| SCHEMBL350765 | 0.79 | GRN (0.71) | GRNSORT1KDM4EMAPTLMNA | |
| SCHEMBL12868385 | 0.79 | GRN (0.71) | GRNSORT1KDM4EMAPTLMNA | |
| Hydrochloric Acid SCHEMBL8760885 | 0.79 | GRN (0.96) | GRNSORT1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514679-A | Palladium-catalyzed sp with low-cost and high-efficiency quaternary ammonium nitrate as oxidant 2 And sp (sp) 3 Carbon hydrogen bond alkenylation method | 南京工业大学 | 2023-08-01 | — | — | CN | disclosed |