Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GRN | P28799 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12612042 | 0.87 | KDM4E (0.45) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| SCHEMBL29045409 | 0.85 | GRN (0.67) | KDM4EGRNSORT1ALDH1A1HSD17B10 | |
| SCHEMBL3711515 | 0.83 | NPC1 (0.48) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| SCHEMBL28957395 | 0.82 | NOTUM (0.40) | KDM4EALDH1A1CYP3A4HSD17B10POLB | |
| SCHEMBL24133713 | 0.81 | NPC1 (0.48) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| SCHEMBL13064210 | 0.81 | KDM4E (0.51) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| SCHEMBL17920 | 0.81 | GRN (0.71) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8932269 | 0.79 | GRN (0.69) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| SCHEMBL951323 | 0.79 | KDM4E (0.50) | KDM4EGRNSORT1ALDH1A1CYP3A4 | |
| SCHEMBL17732 | 0.79 | KDM4E (0.50) | KDM4EGRNSORT1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230285377-A1 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. | 2023-09-14 | — | — | US | disclosed |
| CN-109689629-B | Process for preparing 3-fluoroalkyl-5-pyrazole carboxylic acid esters and 3-fluoroalkyl-5-pyrazole carboxylic acids | 拜耳作物科学股份公司 | 2022-11-29 | — | — | CN | disclosed |
| EP-3515893-B1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2020-10-21 | — | — | EP | disclosed |
| EP-3515893-B1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2020-10-21 | — | — | EP | disclosed |
| US-10556867-B2 | Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-11 | — | — | US | disclosed |
| US-10556867-B2 | Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-11 | — | — | US | disclosed |
| EP-3515893-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | Bayer CropScience Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20190225586-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| US-20190225586-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| WO-2018054807-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018054807-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230285377-A1 | KCNT1 INHIBITORS AND METHODS OF USE | KCNT1, KCNT2, KCNQ2 | KDM4E 1355/4885GRN 1516/4885SORT1 2256/4885 |
| US-20190225586-A1 | PROCESS FOR PREPARING 3-FLUOROALKYL-5-PYRAZOLECARBOXYLATES AND 3-FLUOROALKYL-5-PYRAZOLECARBOXYLIC ACIDS | KYAT3, PFKFB3, PFKFB1 | KDM4E 589/4885GRN 2469/4885SORT1 3747/4885 |
| US-10556867-B2 | Process for preparing 3-fluoroalkyl-5-pyrazolecarboxylates and 3-fluoroalkyl-5-pyrazolecarboxylic acids | KYAT3, PFKFB3, PFKFB1 | KDM4E 589/4885GRN 2469/4885SORT1 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.