SCHEMBL29045541

SCHEMBL29045541

CCNc1nc2ccc(C=O)cc2o1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.44
ABL1 P00519 1/20 0.37
CYP2A6 P11509 1/20 0.35
ALDH1A3 P47895 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
S1PR3 Q99500 1/20 0.34
TP53 P04637 1/20 0.34
FBP1 P09467 1/20 0.34
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
PTK2B Q14289 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8034874 0.78 MAPT (0.56) ELANENPC1RAB9ASMN1; SMN2TP53
SCHEMBL9380547 0.77 ELANE (0.40) ELANENPC1RAB9ASMN1; SMN2TP53
SCHEMBL9380550 0.77 ELANE (0.40) ELANENPC1RAB9ASMN1; SMN2TP53
SCHEMBL2841557 0.75 TTR (0.49) ELANENPC1RAB9AMAPTKDM4E
SCHEMBL12755430 0.75 CSNK1D (0.49) ELANEABL1S1PR3FBP1MAPT
SCHEMBL4242492 0.74 POLB (0.48) ELANECYP2A6NPC1RAB9ASMN1; SMN2
SCHEMBL14500973 0.74 NPC1 (0.53) NPC1RAB9ASMN1; SMN2TP53MAPT
SCHEMBL9379570 0.74 ELANE (0.33) ELANENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL9379577 0.74 ELANE (0.33) ELANENPC1RAB9ASMN1; SMN2MAPT
SCHEMBL9380881 0.74 ELANE (0.36) ELANEMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514788-B Chromone mTOR inhibitor, and pharmaceutical composition and application thereof 贵州医科大学 2025-05-13 CN disclosed
CN-116514788-A Chromone mTOR inhibitor, and pharmaceutical composition and application thereof 贵州医科大学 2023-08-01 CN disclosed