Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29045932 | 1.00 | BCHE (0.46) | BCHEGSK3BGABRA1GABRG2GABRB3 | |
| SCHEMBL29986196 | 1.00 | BCHE (0.46) | BCHEGSK3BGABRA1GABRG2GABRB3 | |
| SCHEMBL29045951 | 0.87 | PARP14 (0.54) | BCHEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29045946 | 0.87 | PARP14 (0.54) | BCHEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29045901 | 0.85 | BCHE (0.49) | BCHEPARP14BRAFDYRK1AL3MBTL1 | |
| SCHEMBL29986612 | 0.85 | HTR2C (0.44) | BCHEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29045890 | 0.85 | HTR2C (0.44) | BCHEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL29986906 | 0.85 | BCHE (0.49) | BCHEPARP14BRAFDYRK1AL3MBTL1 | |
| SCHEMBL29045899 | 0.85 | BCHE (0.49) | BCHEPARP14BRAFDYRK1AL3MBTL1 | |
| SCHEMBL29045894 | 0.85 | HTR2C (0.44) | BCHEGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304597-B | Beta-carboline compounds and application thereof in preparation of medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2023-10-20 | — | — | CN | disclosed |
| CN-115304597-A | Beta-carboline compounds and application thereof in preparing medicines for treating or preventing tumor diseases | 中国科学院深圳先进技术研究院 | 2022-11-08 | — | — | CN | disclosed |