Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288858 | 1.00 | CPB1 (0.69) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL30288647 | 1.00 | CPB1 (0.69) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL29046605 | 1.00 | CPB1 (0.69) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL29046618 | 1.00 | CPB1 (0.69) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL31045416 | 0.92 | CPB1 (0.75) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL17440204 | 0.91 | CPB1 (0.74) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL10916791 | 0.90 | CPB1 (0.77) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL10916786 | 0.90 | CPB1 (0.77) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL24515782 | 0.86 | CPB1 (0.67) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL30288635 | 0.86 | CPB1 (0.67) | CPB1ALDH1A1TSHRCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547270-A | 4- (2-fluoro-4-methoxy-5-3- (((1-methylcyclobutyl) methyl) carbamoyl) bicyclo [2.2.1] hept-2-yl) carbamoyl) phenoxy) -1-methylcyclohexane-1-carboxylic acid derivatives and similar compounds as RXFP1 modulators for the treatment of heart failure | 阿斯利康(瑞典)有限公司 | 2023-08-04 | — | — | CN | disclosed |