Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12677569 | 0.91 | MDM4 (0.49) | MDM4TP53CASP3KMT2AEPHX2 | |
| SCHEMBL29367497 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL29624621 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL119575 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL119565 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL29355082 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL598209 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| SCHEMBL30802551 | 0.91 | MDM4 (0.56) | MDM4TP53CASP3 | |
| Fluoride SCHEMBL7155195 | 0.90 | MDM4 (0.55) | MDM4TP53CASP3 | |
| SCHEMBL6987530 | 0.90 | MDM4 (0.48) | MDM4TP53CASP3KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114380880-B | Fmoc-amino acid modified 20 (S) -protopanoxadiol derivative and preparation method and application thereof | 吉林大学 | 2023-06-23 | — | — | CN | disclosed |