SCHEMBL29367497

SCHEMBL29367497

CC(C)(C)OC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.56
TP53 P04637 2/20 0.56
CASP3 P42574 2/20 0.53
MDM2 Q00987 3/20 0.50
TLR2 O60603 2/20 0.50
TNF P01375 1/20 0.50
SLC17A5 Q9NRA2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598209 1.00 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL119565 1.00 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL30802551 1.00 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL29355082 1.00 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL119575 1.00 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
SCHEMBL29624621 1.00 MDM4 (0.56) MDM4TP53CASP3MDM2TLR2
Fluoride SCHEMBL7155195 0.99 MDM4 (0.55) MDM4TP53CASP3MDM2TLR2
SCHEMBL30562127 0.96 MDM4 (0.53) MDM4TP53CASP3MDM2TLR2
SCHEMBL29400671 0.92 MDM4 (0.52) MDM4TP53CASP3MDM2TLR2
SCHEMBL9072218 0.91 MDM4 (0.50) MDM4TP53CASP3MDM2TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529031-A Cyclic peptide derivative and preparation method and application thereof 润辉生物技术(威海)有限公司 2025-02-28 CN claimed
CN-117343128-A Synthesis method of buserelin 成都君诚康正生物科技有限公司 2024-01-05 CN claimed
CN-111233980-B Fragment method synthesis method of goserelin 南京礼威生物医药有限公司 2023-08-01 CN claimed
WO-2022266927-A1 LIRAGLUTIDE VARIANT, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 深圳翰宇药业股份有限公司 2022-12-29 WO claimed
CN-113999289-A Preparation method of goserelin 杭州信海医药科技有限公司 2022-02-01 CN claimed
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP disclosed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US disclosed
US-12616761-B2 CXCR4-targeting compounds THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2026-05-05 US disclosed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US disclosed
EP-4725957-A1 GROUP OF CYCLIC ALKALINE LIPOPEPTIDE COMPOUNDS, AND PREPARATION METHOD THEREFOR AND USE THEREOF Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) 2026-04-15 EP disclosed
EP-4720097-A1 PEPTIDES WITH LIPOLYTIC, ANTI-LIPOGENIC, ANTIFIBROTIC AND ANTI-INFLAMMATORY ACTIVITY Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca (ES) 2026-04-08 EP disclosed
EP-4696686-A1 FAPI THERANOSTIC COMPOUNDS ASSEMBLED WITH TETRAZINE LIGATION Tetrakit Technologies ApS (DK) 2026-02-18 EP disclosed
WO-2022061924-A1 GLP-1R/GCGR DUAL-TARGET AGONIST PEPTIDE DERIVATIVES FOR TREATMENT OF VIRAL HEPATITIS-RELATED HEPATIC FIBROSIS 深圳市图微安创科技开发有限公司 2022-03-31 WO disclosed
WO-2022054062-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2022-03-17 WO disclosed
EP-3966234-A1 VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF Consejo Superior De Investigaciones Científicas (ES) 2022-03-16 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-3953333-A1 NOVEL CYCLIC TREX1 INHIBITORS Venenum Biodesign, LLC (US) 2022-02-16 EP disclosed
CN-113999289-A Preparation method of goserelin 杭州信海医药科技有限公司 2022-02-01 CN disclosed
CN-113999289-A Preparation method of goserelin 杭州信海医药科技有限公司 2022-02-01 CN disclosed
WO-2022018264-A1 SILICON-CONTAINING LIGAND COMPOUNDS Technische Universität München (DE) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 MDM4 1931/4885TP53 805/4885CASP3 1335/4885
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN GLP1R, ALB, GIPR MDM4 4874/4885TP53 2182/4885CASP3 1790/4885
US-12616761-B2 CXCR4-targeting compounds CXCR4, CXCR2, CXCR3 MDM4 3817/4885TP53 1733/4885CASP3 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.