SCHEMBL2904718

SCHEMBL2904718

C=C(C)C(=O)OCCCC[SiH](OCCCC)OCCCC

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.65
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
THRB P10828 1/20 0.45
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.39
ATM Q13315 1/20 0.37
NAAA Q02083 1/20 0.36
RAD52 P43351 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
EPHX1 P07099 1/20 0.34
ACHE P22303 6/20 0.33
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL144127 0.95 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2404019 0.92 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5699021 0.90 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL17002616 0.87 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL98029 0.87 TSHR (0.59) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9757145 0.86 TSHR (0.54) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19409171 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16286969 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL29432640 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1
SCHEMBL19409198 0.86 TSHR (0.62) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853645-B1 AQUEOUS CURABLE SILANE/POLYMER COMPOSITIONS CROMPTON CORP (US) 2004-04-14 EP claimed
US-6319982-B1 POLYMER/CROSSLINKING SYSTEM WHICH IS COMPOSED OF A SELF CROSSLINKING RESIN COMPRISED OF A SILICONE FLUID MODIFIED WITH PENDANT OR TERMINAL SILANES CONTAINING HINDERED ALKOXY GROUPS CK WITCO CORPORATION 2001-11-20 US claimed
EP-0985718-A2 Use of emulsified coupling agents as primers to improve adhesion of sealants, adhesives and coatings CK WITCO CORPORATION (US) 2000-03-15 EP claimed
US-6037008-A APPLYING AN ADHESION PROMOTING ORGANOSILANE PRIMER COMPOSITION TO A SUBSTRATE SURFACE, APPLYING A CURABLE SEALANT, ADHESIVE OR COATING FORMULATION TO THE PRIMED SUBSTRATE, AND ALLOWING SAID SEALANT, ADHESIVE OR COATING TO CURE CK WITCO CORPORATION 2000-03-14 US claimed
US-5686523-A OF A SATURATED ALKOXY SILANE, AN EMULSIFIER, WATER AND A WATER DISPERSIBLE OR EMULSIFIED POLYMER CONTAINING AN ALKOXY SILANE FUNCTIONAL GROUP OSI SPECIALTIES, INC. (US) 1997-11-11 US claimed
EP-1194475-B1 WATERBORNE SILICONE ADHESIVES, SEALANTS AND COATINGS MOMENTIVE PERFORMANCE MAT INC (US) 2010-08-04 EP disclosed
EP-1194219-B1 HYDROLYZABLE SILANE EMULSIONS AND METHOD FOR PREPARING THE SAME MOMENTIVE PERFORMANCE MAT INC (US) 2008-03-12 EP disclosed
EP-1036834-B1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL NIPPON CATALYTIC CHEM IND (JP) 2006-06-14 EP disclosed
EP-0853645-B1 AQUEOUS CURABLE SILANE/POLYMER COMPOSITIONS CROMPTON CORP (US) 2004-04-14 EP disclosed
US-6372355-B1 MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-16 US disclosed
EP-1194219-A1 HYDROLYZABLE SILANE EMULSIONS AND METHOD FOR PREPARING THE SAME Crompton Corporation (US) 2002-04-10 EP disclosed
US-6319982-B1 POLYMER/CROSSLINKING SYSTEM WHICH IS COMPOSED OF A SELF CROSSLINKING RESIN COMPRISED OF A SILICONE FLUID MODIFIED WITH PENDANT OR TERMINAL SILANES CONTAINING HINDERED ALKOXY GROUPS CK WITCO CORPORATION 2001-11-20 US disclosed
US-5344890-A Copolymer of alkoxysilyl acrylate and epoxy-containing acrylat an amine, amide or urea salt of a super acid as a curing agent NIPPON PAINT CO., LTD. (JP) 1994-09-06 US disclosed
US-5132377-A Storage Stability NIPPON PAINT COMPANY, LIMITED (JP) 1992-07-21 US disclosed
US-5070161-A QUATERNARY AMMONIUM COMPOUND NIPPON PAINT CO., LTD. (JP) 1991-12-03 US disclosed
US-5066722-A Quaternary ammonium sulfonates, hydroxy containing resins, polesters, polylactones, epoxy resins, acrylic resins NIPPON PAINT CO., LTD. (JP) 1991-11-19 US disclosed
US-5025049-A Organic copolymer containing alkoxysilylated monomer, polyalkyl (meth) acrylate, crosslinking agent and ultraviolet absorber SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-06-18 US disclosed
EP-0401770-A2 Heat-latent, cationic polymerization initiator and resin composition containing the same Nippon Paint Co., Ltd. (JP) 1990-12-12 EP disclosed
EP-0385504-A1 Heat-latent curing catalyst and resin compositions containing the same NIPPON PAINT CO., LTD. (JP) 1990-09-05 EP disclosed
EP-0343690-A2 Heat-latent, cationic polymerization initiator and resin compositions containing the same NIPPON PAINT CO., LTD. (JP) 1989-11-29 EP disclosed