Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699021 | 0.95 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL143882 | 0.91 | THRB (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL144127 | 0.88 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2904718 | 0.86 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL237866 | 0.85 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL139125 | 0.84 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL98029 | 0.83 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19409198 | 0.81 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL19409171 | 0.81 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16286969 | 0.81 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025049-A | Organic copolymer containing alkoxysilylated monomer, polyalkyl (meth) acrylate, crosslinking agent and ultraviolet absorber | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-06-18 | — | — | US | disclosed |