SCHEMBL29047360

SCHEMBL29047360

COc1c(C#Cc2cccc(C=O)c2OC)cccc1C=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
SRC P12931 1/20 0.46
ERN1 O75460 4/20 0.46
TLR2 O60603 1/20 0.46
TLR1 Q15399 1/20 0.46
TLR6 Q9Y2C9 1/20 0.46
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 5/20 0.40
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
KMT2A Q03164 1/20 0.39
NFE2L2 Q16236 3/20 0.38
TSHR P16473 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30546704 1.00 CA1 (0.59) CA1CA2SRCERN1TLR2
SCHEMBL29951420 0.85 CA1 (0.56) CA1CA2SRCERN1TLR2
SCHEMBL5667224 0.85 CA1 (0.56) CA1CA2SRCERN1TLR2
SCHEMBL31588086 0.85 CA1 (0.47) CA1CA2SRCERN1TLR2
SCHEMBL286346 0.85 CA1 (0.56) CA1CA2SRCERN1TLR2
SCHEMBL2787203 0.83 CA1 (0.73) CA1CA2SRCERN1TLR2
SCHEMBL3251619 0.82 CA1 (0.45) CA1CA2SRCERN1TLR2
SCHEMBL23108166 0.76 CA1 (0.63) CA1CA2SRCERN1TLR2
O-Veratraldehyde SCHEMBL29923149 0.76 SRC (0.67) CA1CA2SRCERN1TLR2
SCHEMBL1597634 0.76 CA1 (0.63) CA1CA2SRCERN1TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116532160-A Photo/enzyme cascade reaction catalyst based on porous framework material, preparation and application thereof 南开大学 2023-08-04 CN disclosed