Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633995 | 0.84 | KMT2A (0.76) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL11372811 | 0.81 | KMT2A (0.72) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL9479374 | 0.81 | KMT2A (0.72) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL1403354 | 0.80 | HDAC1 (0.80) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL1402884 | 0.80 | HDAC1 (0.80) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL9186300 | 0.79 | KMT2A (0.70) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL94978 | 0.79 | KMT2A (0.70) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL6567551 | 0.79 | KMT2A (0.70) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL4856551 | 0.79 | KMT2A (0.70) | KMT2AHDAC1PGRARHPGD | |
| SCHEMBL1403586 | 0.78 | HDAC1 (1.00) | KMT2AHDAC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947931-B | Thiazole amide compound, preparation method thereof, pharmaceutical composition and application | 中国科学院上海有机化学研究所 | 2023-07-07 | — | — | CN | disclosed |