Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Diphenylacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.48 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylacetic Acid SCHEMBL38022 | 0.88 | SRC (0.62) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL8513250 | 0.88 | SRC (0.62) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL9750917 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL28446280 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL30803718 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL6852183 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL9485695 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL8411440 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL418537 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 | |
| Diphenylacetic Acid SCHEMBL28071099 | 0.85 | SRC (0.59) | CTSDCYP2D6SRCTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535612-A | Polyurethane curing agent | 江苏奥斯佳材料科技股份有限公司 | 2023-08-04 | — | — | CN | claimed |