Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25816599 | 1.00 | GPR119 (0.41) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| SCHEMBL30547518 | 1.00 | GPR119 (0.41) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| SCHEMBL30339030 | 1.00 | GPR119 (0.41) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| Hydrochloric Acid SCHEMBL30338907 | 0.90 | GPR119 (0.35) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| SCHEMBL30338607 | 0.83 | MEN1 (0.37) | — | |
| SCHEMBL25816517 | 0.83 | MEN1 (0.37) | — | |
| SCHEMBL28243039 | 0.83 | GPR119 (0.47) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| SCHEMBL18921324 | 0.83 | GPR119 (0.47) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| SCHEMBL30547535 | 0.82 | GPR119 (0.40) | GPR119KDM4DIRAK4SCD5EGLN2 | |
| SCHEMBL25816597 | 0.82 | GPR119 (0.40) | GPR119KDM4DIRAK4SCD5EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547281-A | Isoxazolidines as RIPK1 inhibitors and uses thereof | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |