Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25816376 | 1.00 | CHRNB2 (0.32) | CHRNB2CHRNA4CHRNA7 | |
| Hydrochloric Acid SCHEMBL29048250 | 0.98 | CHRNB2 (0.32) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL29048286 | 0.98 | CHRNB2 (0.32) | CHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL30338646 | 0.84 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL30339079 | 0.83 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL30338672 | 0.83 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| Trifluoroacetic Acid SCHEMBL30581170 | 0.83 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL22689683 | 0.79 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL31200251 | 0.78 | CYP2A6 (0.43) | CHRNB2CHRNA4 | |
| SCHEMBL25816728 | 0.78 | CYP2A6 (0.43) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547281-A | Isoxazolidines as RIPK1 inhibitors and uses thereof | 赛诺菲 | 2023-08-04 | — | — | CN | disclosed |