SCHEMBL29048485

SCHEMBL29048485

Cc1ccccc1-c1cccc(-c2cccc3c2[nH]c2ccccc23)c1C

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.68
PARP14 Q460N5 15/20 0.53
MAPT P10636 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPK1 P28482 2/20 0.47
NPSR1 Q6W5P4 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GABRP O00591 1/20 0.47
GABRD O14764 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
GABRA1 P14867 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
GABRB1 P18505 1/20 0.47
GABRG2 P18507 1/20 0.47
NFKB1 P19838 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5810425 0.95 KIF11 (0.75) KIF11PARP14MAPTMEN1KMT2A
SCHEMBL23775252 0.90 KIF11 (0.55) KIF11PARP14MAPTMEN1KMT2A
SCHEMBL26373210 0.86 KIF11 (0.62) KIF11PARP14MAPTMEN1KMT2A
SCHEMBL208113 0.85 KIF11 (0.63) KIF11PARP14GABRPGABRDALDH1A1
SCHEMBL29733506 0.85 KIF11 (0.63) KIF11PARP14GABRPGABRDALDH1A1
SCHEMBL29119809 0.84 KIF11 (0.70) KIF11PARP14MAPTMEN1KMT2A
SCHEMBL51674 0.83 KIF11 (0.61) KIF11PARP14GABRPGABRDALDH1A1
SCHEMBL191654 0.83 KIF11 (0.61) KIF11PARP14GABRPGABRDALDH1A1
SCHEMBL30521516 0.83 KIF11 (0.61) KIF11PARP14GABRPGABRDALDH1A1
SCHEMBL31548611 0.82 PARP14 (0.62) KIF11PARP14MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107452775-B Display panel and method of manufacturing the same 三星显示有限公司 2023-08-01 CN disclosed