Glutarate

Glutarate

SCHEMBL29048611

CCCCN.O=C(O)CCCC(=O)O

nearest known ligand 0.67

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC11 Q96DB2 6/20 0.67
TSHR P16473 5/20 0.67
KMT2A Q03164 4/20 0.67
LMNA P02545 2/20 0.67
THRB P10828 2/20 0.67
BLM P54132 2/20 0.67
NPSR1 Q6W5P4 2/20 0.67
GABRR3 A8MPY1 1/20 0.67
GABRP O00591 1/20 0.67
GABRD O14764 1/20 0.67
HDAC3 O15379 1/20 0.67
GABBR2 O75899 1/20 0.67
CYP1A2 P05177 1/20 0.67
GABRA1 P14867 1/20 0.67
GABRB1 P18505 1/20 0.67
GABRG2 P18507 1/20 0.67
GABRR1 P24046 1/20 0.67
GABRB3 P28472 1/20 0.67
GABRR2 P28476 1/20 0.67
SLC6A1 P30531 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamma-Aminobutyric Acid SCHEMBL28030037 0.95 HDAC11 (0.75) HDAC11TSHRKMT2ALMNATHRB
Adipic Acid SCHEMBL27801950 0.95 AKR1B1 (0.71) HDAC11TSHRKMT2ALMNATHRB
Adipic Acid SCHEMBL28533879 0.95 AKR1B1 (0.71) HDAC11TSHRKMT2ALMNATHRB
Octanedioate SCHEMBL27976267 0.93 GPR84 (0.73) HDAC11TSHRKMT2ALMNATHRB
Valeric Acid SCHEMBL27743224 0.93 HDAC11 (0.64) HDAC11TSHRKMT2ALMNATHRB
Octanedioate SCHEMBL28032727 0.93 GPR84 (0.73) HDAC11TSHRKMT2ALMNATHRB
Succinic Acid SCHEMBL28177455 0.92 HDAC11 (0.62) HDAC11TSHRKMT2ALMNATHRB
Octadecylamine SCHEMBL31310134 0.91 GPR84 (0.70) HDAC11TSHRKMT2ALMNATHRB
Palmitic Acid SCHEMBL21834586 0.91 GPR84 (0.77) HDAC11TSHRKMT2ALMNATHRB
Octanoic Acid SCHEMBL1428269 0.91 GPR84 (0.77) HDAC11TSHRKMT2ALMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446770-B Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same 百乐墨水株式会社 2023-08-08 CN disclosed