SCHEMBL29048967

SCHEMBL29048967

CCOC(=O)c1ccc(N2C(=O)CC(=O)NC2=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.62
GAA P10253 3/20 0.62
MAPK1 P28482 1/20 0.61
MAPT P10636 3/20 0.60
ALDH1A1 P00352 7/20 0.59
HPGD P15428 2/20 0.59
HSP90AA1 P07900 1/20 0.59
CACNA1B Q00975 1/20 0.59
APBA1 Q02410 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.52
HSD17B10 Q99714 1/20 0.52
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30533063 0.83 HTT (0.67) HTTGAAMAPK1ALDH1A1HPGD
SCHEMBL14450268 0.82 MAPT (0.57) HTTGAAMAPK1MAPTALDH1A1
SCHEMBL5451457 0.80 ALDH1A1 (0.54) HTTGAAMAPK1MAPTALDH1A1
SCHEMBL16239079 0.79 P2RX4 (0.62) MEN1KMT2A
SCHEMBL4893761 0.78 MEN1 (0.66) HTTGAAMAPK1ALDH1A1HPGD
SCHEMBL8140377 0.78 MEN1 (0.63) MAPTALDH1A1MEN1KMT2ARAB9A
SCHEMBL2953094 0.78 MAPK1 (0.80) HTTGAAMAPK1ALDH1A1HPGD
SCHEMBL8302040 0.76 MAPK1 (0.65) HTTGAAMAPK1MAPTALDH1A1
SCHEMBL125195 0.76 MAPT (1.00) GAAMAPK1MAPTMEN1KMT2A
SCHEMBL8504670 0.75 HTT (1.00) HTTGAAMAPK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116583560-A Rubber composition for hot air crosslinking, crosslinked rubber, and method for producing crosslinked rubber 日油株式会社 2023-08-11 CN disclosed