Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 16/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 8/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633613 | 0.89 | TEK (0.42) | ERN1MAPK10AURKBTEK | |
| SCHEMBL24435876 | 0.89 | TEK (0.42) | ERN1MAPK10AURKBTEK | |
| SCHEMBL29633651 | 0.89 | ERN1 (0.51) | ERN1MAPK10AURKB | |
| SCHEMBL24435934 | 0.89 | ERN1 (0.51) | ERN1MAPK10AURKB | |
| SCHEMBL28557737 | 0.84 | ERN1 (0.43) | ERN1MAPK10AURKBTEK | |
| SCHEMBL29049061 | 0.82 | ERN1 (0.56) | ERN1MAPK10AURKBTEK | |
| SCHEMBL20497845 | 0.80 | ERN1 (0.64) | ERN1MAPK10 | |
| SCHEMBL20497840 | 0.80 | ERN1 (0.64) | ERN1MAPK10 | |
| SCHEMBL25071792 | 0.79 | TEK (0.44) | ERN1MAPK10TEK | |
| SCHEMBL28566090 | 0.79 | TEK (0.44) | ERN1MAPK10TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116583276-A | IRE1 alpha inhibitors and uses thereof | 加利福尼亚大学董事会 | 2023-08-11 | — | — | CN | disclosed |