Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | PIM1 | P11309 | 2/20 | 0.59 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.43 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828894 | 1.00 | HPGD (0.59) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL30442966 | 0.91 | HPGD (0.55) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL31412140 | 0.82 | PIM1 (0.59) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL15421862 | 0.82 | HPGD (0.59) | HPGDKMT2AMEN1CYP1A2MAOA | |
| SCHEMBL15421861 | 0.82 | HPGD (0.59) | HPGDKMT2AMEN1CYP1A2MAOA | |
| SCHEMBL29049322 | 0.81 | PIM1 (0.55) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL2341294 | 0.81 | PIM1 (0.55) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL15281015 | 0.81 | PIM1 (0.55) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL31412078 | 0.81 | PIM1 (0.62) | HPGDPIM1PIM2KMT2AMEN1 | |
| SCHEMBL29049367 | 0.81 | PIM1 (0.62) | HPGDPIM1PIM2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554079-B | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-116554079-A | Histone deacetylase inhibitor and application thereof | 南京市鸿舜医药科技有限公司 | 2023-08-08 | — | — | CN | disclosed |